June 8, 2023

Cyclohexanol and Phenol 5 Best Difference

The explanation of Cyclohexanol and Phenol

Cyclohexanol as well as phenol are two organic compounds that are part of the alcohol family that are distinguished through the existence of an perceived hydroxyl (-OH) group within the chemical formula.

Cyclohexanol is a six-membered cyclic hydrocarbon (cyclohexane) as its backbone. It also has an OH-group that is attached to one of carbon atoms of the ring. Its chemical formula Cyclohexanol is C6H12O which has a molecular mass that is 100.16 g/mol.

Cyclohexanol is a non-colorless liquid that is dissolved at room temperatures with the boiling point at 161.1degC and the density of 0.962 grams per cubic centimeter.

Phenol is, in contrast is a cyclic six-membered hydrocarbon (benzene) with an OH group directly linked to one carbon atom within the ring. Chemical formulas for Phenol is C6H5OH which has a molecular mass of 94.11 mg/mol. Phenol is an crystalline white solid at room temperature, having a melting temperature of 40.5degC and an optimum boiling temperature of 182 degrees Celsius.

Concerning chemical reactivity the -OH molecule in phenol is more acidic in cyclohexanol, due to the stabilization of resonances within the phenoxide ion that is formed following deprotonation. This makes phenol a more powerful acid than cyclohexanol, and alters their characteristics in chemical as well as physical.

What exactly is Cyclohexanol?

Cyclohexanol is a compound of organic origin with its chemical formula HOCH(CH2)5. It is formed by the substitution by a hydrogen atom in the cyclohexane molecule by an hydroxyl group.

Cyclohexanol is an insoluble transparent solid with the odor of camphor. Purely it is able to melt at temperatures close to the temperature of room. The material is manufactured annually in large quantities and is utilized as a precursor for nylon.

                            Figure 1 : Cyclohexanol


The primary route for production for cyclohexanol is process of oxidation of cyclohexane within the air. The catalyst used in this process is with cobalt as its component. This reaction produces cyclohexanone and is the primary feedstock for the adipic acid.

The most important use for cyclohexanol is that it can be used as an ingredient in nylon’s feedstock, as previously mentioned. However it can also be used as a precursor for different plasticizers. Furthermore, cyclohexanol has been proven to be an excellent solvent.

What exactly is Phenol?

Phenol is an organic substance with an chemical formula of HO-C6H5. These are aromatic compounds due to their alcohol rings. Phenol is a white solid, which is flammable. The white solid of Phenol smells sweet that is dark and tarry. Additionally, it’s easily soluble in water because of its Polarity.

It is an acidic compound because of it having a proton that is removable in the hydroxyl group of the phenol. We must also take care when handling phenol solutions to avoid burning.


                     Figure 1 : Phenol  


Phenol is produced through the extraction process of coal tar. The primary method for production is through the use of petroleum as a feedstock. The process for the manufacturing of phenol is called what is known as “Cumene process.”

Phenol is known to be subjected to electrophilic transformation reactions since the electron pairs that make up oxygen are transferred to the structure of the ring. Thus, a wide range of groups, such as halogens, sulfur-containing groups, acyl group such as. could be substituted by the structure of a ring. Phenol can be converted to benzene through distillation zinc dust.

What is the difference between Cyclohexanol and Phenol

Cyclohexanol as well as phenol both organic substances that have certain features, but possess distinct distinctions. The most significant differences between cyclohexanol as well as the phenol are:

Chemical Structure Cyclohexanol contains a six-membered hydrocarbon cyclic (cyclohexane) to form its backbone. It has an -OH group bonded to one carbon atom within the rings.


                                                      figure 03:  Cyclohexanol and Phenol

Phenol is, on the other on the other hand, is six members of cyclic hydrocarbon (benzene) which has an OH group that is directly connected to one carbon atom within the ring. This distinction in the chemical structure of the compound affects their chemical and physical properties.

pH: Phenol has a higher acidity than cyclohexanol, due to the stabilization of resonances in the Phenoxide ion, which is formed upon deprotonation. This makes Phenol more sensitive to acidic environments and could affect the properties of phenol in certain situations.

Physical properties: Cyclohexanol is a colorless liquid at room temperature with a boiling temperature of 161.1degC and the density of 0.962 grams per cubic centimeter. Phenol is, on the other being an ice-white liquid at ambient temperature with a melting temperature of 40.5degC and an 182degC boiling point.

Application: Cyclohexanol is commonly used to dissolve solvents and as a precursor for other chemicals, such as adipic acid that is used for the manufacture of nylon. Phenol has a broad range of uses, such as an ingredient in pharmaceuticals, plastics and dyes, as well as being an antiseptic and disinfectant.

Safety and Health The two compounds cyclohexanol and Phenol could be harmful if they are consumed and inhaled in huge amounts. But phenol is much more poisonous and can lead to severe burns, respiratory issues as well as other health problems If not handled correctly.

The primary distinctions between cyclohexanol and Phenol is their chemical structure as well as their physical properties, acidity applications, as well as security and health considerations. These distinctions make them appropriate for various applications and demand care when handling or using them.


Cyclohexanol as well as phenol can be created by a variety of methods like oxidation or hydrolysis.

A common method of producing Cyclohexanol is by the oxidation of cyclohexane by using air and catalysts such as copper or cobalt. This is referred to as the process of air oxidation and is the process of changing the cyclohexane into cyclohexanol as well as which is separated using fractional distillation.

Phenol however, in contrast can be made by various methods. The most popular method is the Cumene process. It involves the reaction of propylene with benzene when they are in contact with catalysts like aluminum chloride to make Cumene. Cumene is then oxidized, resulting in Acetone and phenol, which can be separated through distillation.

Another way to produce phenol is by the hydrolysis of chlorobenzene that involves the reaction of chlorobenzene and sodium hydroxide in water to create sodium chloride and phenol.

Both cyclohexanol as well as phenol are also produced by removing coal tar, a product of coal processing, by a variety of extraction and purification procedures. But, these techniques aren’t as widely used because of the availability more efficient and economical manufacturing methods.

Toxicity and Health Impacts

The effects of toxicity and health are crucial concerns in the work with Cyclohexanol or Phenol. Both chemicals be harmful when handled incorrectly or inhaled.

A. Cyclohexanol

Toxicity and health-related effects: Cyclohexanol can irritate the eyes as well as the skin and respiratory tract when in the contact with or through inhalation. In the event of repeated or prolonged exposure, it can result in dermatitis and damage to the lung, as well as liver damage. Consumption of Cyclohexanol may cause abdominal discomfort nausea vomiting as well as central nervous system depression.

Safety measures: Proper ventilation and personal protective equipment, like gloves and goggles, must be worn when working with Cyclohexanol. spills must be cleaned promptly and the area must be ventilated. Cyclohexanol is best stored in a dry, cool and well-ventilated space far from any substances that are incompatible and heat sources.

B. Phenol

Health and Toxicity: Phenol can be corrosive to the eyes, skin and respiratory tract on the contact with or through inhalation. It may cause burns tissues damage, and respiratory discomfort. The consumption of Phenol could cause gastrointestinal discomfort, chemical burns along with central nervous system weakness.

Safety precautions Personal protective equipment like goggles, gloves and a respirator must be worn when working with Phenol. The spills must be contained and the work area must be adequately ventilated. Phenol is best stored in a dry, cool well-ventilated location free of incompatible materials and heating sources.

C. Comparison

Comparison of the health and toxicity impacts that result from Cyclohexanol and Phenol both Cyclohexanol and Phenol can cause irritation on contact or inhalation, and the ingestion of either substance can result in severe health problems. But, Phenol is generally considered to be more poisonous and harmful than Cyclohexanol and therefore requires greater safety precautions.

It is crucial to be aware of the potential health risks that can be posed by the use of Cyclohexanol and Phenol and to be aware of the necessary safety precautions needed to limit the chance of being exposed.

Summary – Cyclohexanol Vs Phenol

The most distinctive characteristic of phenol is its aromatic chemical structure that is not present in the cyclohexanol. The primary distinction between cyclohexanol and is that cyclohexanol’s is an Unaromatic cyclic compound unlike phenol, which is an aromatic cycle compound.